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A freshly baked keto chicken casserole with melted cheese and herbs on top, served in a white baking dish.

keto chicken casserole

Prep Time 10 minutes
Cook Time 30 minutes
Total Time 40 minutes
Course Main Course
Cuisine American
Calories 365 kcal

Ingredients
  

Protein-Packed Chicken Base:

  • 4 boneless skinless chicken breasts (8 each): Lean yet juicy, these form the hearty backbone of the casserole. Swap with chicken thighs for extra richness!
  • Avocado oil spray: A keto-friendly high-smoke-point oil for golden searing without sticking.

Creamy Zesty Sauce:

  • ¼ –⅓ cup mayonnaise + sour cream: A luxe low-carb duo that adds tangy creaminess without heavy carbs.
  • 1 tbsp Dijon mustard: Lifts the sauce with a subtle sharpness.
  • 1 tbsp fresh garlic minced: For aromatic depth.
  • ½ tsp dried thyme + ½ tsp paprika + ¼ tsp cayenne: A trifecta of smoky herbal, and spicy warmth.
  • 1 cup sharp cheddar divided: Melts into gooey pockets of flavor while keeping carbs in check.

Crunchy, SavoryTopping:

  • ¼ cup scallions green parts only: Fresh, mild oniony brightness.
  • ¼ cup bacon bits: Adds salty crispy contrast—opt for sugar-free bacon for strict keto!

Instructions
 

Prep & Roast the Chicken

  • Preheat oven to 450°F. Line a rimmed baking sheet with foil and lightly coat with avocado oil spray.
  • Arrange chicken breasts in a single layer on the sheet. Mist tops with oil, then season evenly with salt and black pepper.
  • Bake for 18-20 minutes until internal temp reaches 165°F. Tip: For extra-tender chicken, cover loosely with foil after 15 minutes.

Whisk the Creamy Sauce

  • While chicken cooks, grease a 9×13-inch (2-quart) casserole dish and set aside.
  • In a large bowl, mix mayonnaise, sour cream, Dijon mustard, minced garlic, salt, and pepper. Add thyme, paprika, cayenne, and ½ cup of shredded cheddar. Stir until smooth and fully incorporated.

Shred & Mix

  • Let chicken rest 5 minutes after baking. Reduce oven temp to 400°F (keep it on!).
  • Dice or shred chicken into bite-sized pieces using two forks. Shortcut: Use pre-cooked rotisserie chicken here!
  • Toss warm chicken in the sauce mixture until evenly coated.

Assemble & Bake

  • Transfer saucy chicken to the greased casserole dish. Sprinkle remaining ½ cup cheddar on top.
  • Bake at 400°F for 8-10 minutes, just until cheese melts and edges bubble.

Finish & Serve

  • Remove from oven and immediately garnish with scallions and bacon bits for a salty-crunchy contrast.
  • Serve hot alongside a crisp salad or steamed greens. Pro tip: Let leftovers cool before storing—reheat gently to keep the sauce creamy!